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BETA-CASOMPORPHINS (BCMs) - Production and Absorption


 

Enzymatic release of neocasomorphin and beta-casomorphin from bovine beta-casein.
Jinsmaa, Y & Yoshikawa, M. (1999). Peptides V20(8), pp 957-962.

Demonstration of beta-casomorphin immunoreactive materials in in vitro digests of bovine milk and in small intestine contents after bovine milk ingestion in adult humans.
Svedberg J, de Haas J, Leimenstoll G, Paul F, Teschemacher H. Peptides. 1985 Sep-Oct;6(5):825-30.

Casein peptide release and passage to the blood in humans during digestion of milk or yogurt
Chabance B, Marteau P, Rambaud JC, Migliore-Samour D, Boynard M, Perrotin P, Guillot R, Jolles P, Fiat AM 1998.. Biochimie 80(2), pp 155-165.

beta-Casomorphin-immunoreactivity in the brain stem of the human infant.
Pasi A, Mahler H, Lansel N, Bernasconi C, Messiha FS.1993 Res Commun Chem Pathol Pharmacol. 80(3):305-22.

Demonstration of a beta-casomorphin immunoreactive material in the plasma of newborn calves after milk intake.
Umbach M, Teschemacher H, Praetorius K, Hirschhauser R, Bostedt H. 1985. Regul Pept. Nov 7;12(3):223- 30. • Link:

ß-Casomorphin Induces Fos-Like Immunoreactivity in Discrete Brain Regions Relevant to Schizophrenia and Autism.
Zhongjie Sun, J. Robert Cade, Melvin J. Fregly, R. Malcolm Privette. University of Florida, USA. Autism, Vol. 3, No. 1, 67-83 (1999).

In vitro penetration of des-tyrosine1-D-phenylalanine3-beta-casomorphin across the blood-brain barrier.
Stark H, Van Bree JB, de Boer AG, Jaehde U, Breimer DD. (1992) Peptides. 13(1):47-51.

Saturable transport of peptides across the blood-brain barrier.
Banks WA, Kastin AJ. (1987) Life Sci. 41(11):1319-38.